Amendment to [Section 2.05]. [Section 2.05(a)] is amended by deleting the phrase “the Swing Line Lender agrees to make Swing Line Loans to the Company” in the first sentence thereof and replacing it with “the Swing Line Lender may in its sole discretion make Swing Line Loans to the Company”.

Amendment to [Section 2.2A] of the Agreement. The second sentence in [Section 2.2A] is hereby deleted and replaced with the following two sentences:

Amendment to [Section 2.1(H)(i)] of the Agreement. [Section 2.1(H)(i)] of the Agreement is hereby amended by adding the following sentence immediately after the first sentence of such Section:

Amendment to [Section 2.22]. [Sections 2.22.1, 2.22.2 and 2.22.3]3]3] of the Credit Agreement are hereby amended and restated in their entirety to read as follows:

[Section 2.12(b)(ii)] of the Credit Agreement is hereby amended and restated in its entirety to read as follows:

[Section 2.5(a)] of the Sellers Disclosure Letter sets forth:

[Section 2.8(a)] of the Sellers Disclosure Letter sets forth a list of the following Contracts to which an Acquired Company is a party or otherwise bound, which shall be deemed to constitute “Material Contracts”, true and correct copies of which (including all exhibits, schedules and amendments thereto) have been made available to Purchaser prior to the date hereof:

[Section 2.13(a)] of the Sellers Disclosure Letter sets forth a true and complete list of each material Seller Benefit Plan as of the Effective Date.

[Section 2.14(a)] of the Sellers Disclosure Letter sets forth a list of the Acquired Company Employees as of the Effective Date, which list shall be amended prior to the Closing to reflect the addition of any employee who is hired by, or transferred to, an Acquired Company following the Effective Date and the removal of any individual whose employment with an Acquired Company is terminated prior to the Closing, and any employee of an Acquired Company whose work relates primarily to Mitchell (the “Mitchell Employees”) and whose employment is transferred from an Acquired Company to an Affiliate of the Sellers (other than the Acquired Companies) prior to the Closing Date. Sellers have provided to Purchaser the following information on a confidential basis: each Acquired Company Employee’s current base salary or wage rate and target bonus for the 2021 fiscal year (if any), position, date of hire (and, if different, years of recognized service), status as exempt or non-exempt under the Fair Labor Standards Act, and whether such Acquired Company Employee is on leave status, which information shall be updated prior to Closing to reflect changes made consistent with the first sentence of this [Section 2.14(a)].

[Section 2.08(b)] shall be deleted in its entirety, and the following new [Section 2.08(b)] shall be inserted in place thereof:

[Section 2.8] is amended by deleting the last four sentences of such Section.

[Section 2.2] # shall be terminated and fail as of the date of this amendment. No additional consideration shall be payable related to the future performance of the Company.

[Section 2.9.5] shall apply upon In Vivo Proof-of-Concept (as defined in [Section 2.9.5]) being achieved for a [Schedule 1.93] Target.

[Section 2.2] of the Credit Agreement is hereby amended and restated in its entirety as follows:

[Section 2.5] of the Loan Agreement is hereby amended by deleting the word “and” immediately following [Section 2.5(c)], replacing “.” at the end of [Section 2.5(d)] with “; and” and adding [Section 2.5(e)] thereto as follows:

[Section 2.16] (Increase in Commitments) of the Credit Agreement is hereby amended by replacing the lead in phrase “At any time prior to the Business Day immediately preceding the Maturity Date…” with the phrase “At any time after the Amendment No. 1 Effective Date but prior to the Business Day immediately preceding the Maturity Date….”

[Section 2.04(b)] of the Credit Agreement is hereby amended by adding at the end of the first sentence of such [Section 2.04(b)] and immediately before the period: “; provided that,

[Section 2.04(c)] of the Credit Agreement is hereby amended by replacing the reference to “​” in such [Section 2.04(c)] with a reference to “​”.

[Section 2.2] of the Collateral Agreement is restated in its entirety as follows:

[Section 2.3] of the Collateral Agreement is amended to replace each reference to “Subsidiary Borrower Obligations” appearing therein with “Obligations”.